Functional human GRIN2B promoter polymorphism and variation of mental processing speed in older adults
نویسندگان
چکیده
منابع مشابه
Functional human GRIN2B promoter polymorphism and variation of mental processing speed in older adults
We investigated the role of a single nucleotide polymorphism rs3764030 (G>A) within the human GRIN2B promoter in mental processing speed in healthy, cognitively intact, older adults. In vitro DNA-binding and reporter gene assays of different allele combinations in transfected cells showed that the A allele was a gain-of-function variant associated with increasing GRIN2B mRNA levels. We tested t...
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ژورنال
عنوان ژورنال: Aging
سال: 2017
ISSN: 1945-4589
DOI: 10.18632/aging.101228